|Title||Professor Jang Jin-Ho’s Research Team Increases Depth of Penetration of Light into Body Tissue Using Ultrasonic Waves|
Professor Jang Jin-Ho’s Research Team Increases Depth of Penetration of Light into
Body Tissue Using Ultrasonic Waves
- Original technology capable of overcoming the limits of existing optical imaging and
light therapy technologies; expected to create a new market -
<(Left) Prof. Jang Jin-Ho, (right) Kim Hye-min>
Professor Jang Jin-Ho’s research team developed a technology capable of increasing the depth of penetration of light into body tissue using ultrasonic waves. In other words, the team proved that the depth of penetration of light can be increased by temporarily changing the properties of the medium where light passes. The results of the research were published as a thesis on November 23rd on Scientific Reports, an international journal issued by Nature Publishing Group.
The research increased the depth of penetration of light by temporarily changing the optical scattering property of the body tissue using ultrasonic waves and is expected to improve the performance of the existing optical imaging and light therapy technologies (e.g. confocal microscope, photoacoustic imaging, OCT, photothermal therapy, photodynamic therapy, etc.) and extend the scope of clinical application. In addition, as the present technology is a new concept and unique technology capable of overcoming the limits of the existing optical imaging and light therapy technologies, if commercialized it is expected to not only easily enter the existing optical imaging and light therapy markets and gain market share, but also create a new market and lead related businesses.
- Title: Increased light penetration due to ultrasound-induced air bubbles in optical scattering media
- Author: Jang Jin-ho (Corresponding author, Professor at Sogang University), Kim Hye-min (First author, Doctor’s course at Sogang University)
- Optical scattering: Physical phenomenon in which light changes its direction of progress upon collision with particles
- Optical imaging: Technology that comprises radiating light onto the body tissue and, using physical phenomena such as scattering, absorption, reflection, or refraction of light inside the body tissue, providing the structural, molecular, or biochemical information of the body tissue
- Light therapy: Therapies such as photothermal therapy, which uses the phenomenon in which the temperature of a lesion tissue rises when it absorbs the thermal energy of radiated light and the lesion tissue dies when its temperature increases over 60 degrees; and photodynamic therapy, which uses the phenomenon in which the injection of a photosensitizer, which is reactive to light, into a lesion generates active oxygen by the interaction between the photosensitizer and light, and the generated active oxygen destroys the lesion
[Fig 1] Concept diagram of the present technology and its performance verification result using a body tissue-simulating phantom
[Fig 2] Performance verification result of the present technology using a chicken breast